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Mass-Tagged Nucleic Acids for Effective Industrialization of RNA Therapeutics
Opportunity RNA-based therapeutics, such as mRNA vaccines and miRNA drugs, are rapidly transforming modern medicine. However, the manufacturing and distribution of these complex molecules present significant quality assurance (QA) and quality control (QC) challenges. Issues such as degradation, incomplete transcripts, sequence variability, and contamination...
Inventor(s): Marie Migaud, Faisal Hayat
Category(s): All Technologies, Cancer Therapeutics, Medical Device or Method, Therapeutics, Biomarkers
Improved Radio Frequency Based Device for Noninvasive Skin Blood Flow Measurement
Opportunity Accurately measuring skin blood flow is essential for diagnosing and managing a wide range of medical conditions, including vascular disorders, wound healing, and peripheral circulation issues. Current measurement methods are often slow, expensive, and cumbersome, limiting their use in routine clinical care or health monitoring. Existing...
Inventor(s): David Nelson, Christopher Francis, Saeed Latif, Joshua Keller
Category(s): All Technologies, Medical Device or Method, Engineering Device or Method
Fire-Resistant Composites for Extreme Temperature Applications
Opportunity Fire safety is one of the most significant challenges for polymer matrix composites (PMC) and ceramic matrix composites (CMC), which are widely used in aerospace, defense, automotive, and energy applications. Conventional composites, while lightweight and strong, degrade rapidly under extreme heat. Current strategies to improve fire resistance...
Inventor(s): Kuang-Ting Hsiao
Category(s): All Technologies, Composite Materials, Engineering Device or Method, Functionalized Materials
Metabolomic Biomarkers Predict Long-term Physical Function in Survivors of Acute Respiratory Failure
Opportunity Acute respiratory failure (ARF) is a life-threatening condition requiring intensive care, often leaving survivors with lasting physical impairments long after hospital discharge. Many patients develop muscle weakness, limited mobility, and reduced quality of life, which can persist for months or years. Currently, there are few reliable ways...
Inventor(s): Raymond Langley, Ryan Benton, Adeyeye Haastrup
Category(s): All Technologies, Biomarkers, Medical Device or Method, Screening Tests
Adaptable Cueing Trainer for Physical Therapy, Training, and Rehabilitation
Opportunity Proper technique is critical for effective rehabilitation and strength training, particularly for upper extremity exercises that restore mobility and prevent injury. In clinical and athletic settings, therapists and coaches often must supervise multiple patients or athletes at once, making it difficult to provide continuous individualized...
Inventor(s): Kevin Strehler, Shawn Drake
Category(s): All Technologies, Medical Device or Method, Therapeutics
Agnodice: AI-Driven Interactive Learning Platform
Opportunity Traditional classroom and online instruction often face challenges in adapting to the individual needs of students. While lectures, case studies, and written exercises provide structure, they cannot always replicate the dynamic, real-time scenarios students may face in professional practice—particularly in fields requiring patient...
Inventor(s): Bhushan Lohar
Category(s): All Technologies, Medical Device or Method, Software
Spectral Illumination Device Using Light-Emitting Diode (LED) Arrays
OPPORTUNITY Reflectance and Fluorescence imaging are used in numerous medical and research applications, specifically endoscopic cancer screening. White light endoscopy (WLE) is the standard approach for colon cancer screening. However, traditional WLE relies on native tissue contrast (reflectance), and lacks specificity. Autofluorescence imaging (AFI)...
Inventor(s): Silas Leavesley
Category(s): Medical Device or Method, All Technologies
Flexible Bit Truncation Technology for Enhanced Device Efficiency and Machine Learning
Opportunity The modern world thrives on data. From personal devices like smartphones and wearables to specialized systems such as building monitors and smart appliances, data is collected, stored, and processed on a massive scale. Efficient handling of this data is critical, especially as tasks like video streaming, AI-driven applications, and machine...
Inventor(s): Na Gong, William Oswald, Jinhui Wang
Category(s): Engineering Device or Method, Software, All Technologies
Method and Kit to Detect Bacterial Infections in Blood and Urine
Opportunity Contributing to approximately $6 billion in direct health care costs each year, Urinary Tract Infections (UTIs) are the second most common infectious disease worldwide. While UTIs can range wildly in severity, they contribute significantly to cases of hospital sepsis: a life-threatening medical event caused by highly progressed infections....
Inventor(s): Allyson Shea, Rachel Fleck
Category(s): All Technologies, Biomarkers, Medical Device or Method
Accurate Tracking and Measurement of Intercellular Mitochondrial Transfer
Opportunity Mitochondria are commonly referred to as the powerhouse of the cell, and any change in mitochondrial function can drastically alter normal cell function. Diseases including neurodegeneration and cancer have been linked to changes in mitochondrial transfer between cells, which can weaken the functioning of healthy cells. Although studying...
Inventor(s): Simon Grelet, Greg Hoover
Category(s): All Technologies, Cancer Therapeutics, Research Tools, Screening Tests
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