University of South Alabama

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Multi-Well Plate System to Assess Cellular Mechanobiology
OPPORTUNITY In a sheet of endothelial cells, the cellular response to physical and chemical stimuli is often regulated uniquely by the mechanical microenvironment of the cell. However, the mechanical microenvironment which is composed of mechanical stretch, fluid pressure and shear stress, is not static. Monolayer stress microscopy (MSM) has enable...
Inventor(s): Dhananjay Tambe, Neel Patel
Category(s): Engineering Device or Method, Research Tools, All Technologies
Methods for Establishing Mammalian Cell Lines with Altered Mitochondrial DNA Copy Number
OPPORTUNITY Reduced mitochondria DNA (mtDNA) copy number is associated with mitochondrial disease, which is incurable, progressive, and often fatal in early childhood. Currently, unavailability of an effective means to manipulate mtDNA copy number in cells slows progress in our understanding of the mechanisms by which mtDNA deletion contributes to ...
Inventor(s): Mikhail Alexeyev, Domenic Spadafora
Category(s): Cell Line, Research Tools, All Technologies
Biosynthesis of Silver Nanoparticles Using Plant Extracts
OPPORTUNITY The emergence of nanosilver materials in anti-microbial consumer goods and medical products is a major growth driver in the nanosilver market; a growth that is expected to continue from US$1.1 billion in 2015 to around US$2.45 billion by 2022. To meet these needs, more than five hundred tons of silver nanoparticles (AgNP) are synthesize...
Inventor(s): Sumit Arora, Om Jha, Zohaib Ijaz, Yousef Omar
Category(s): All Technologies, Engineering Device or Method, Research Tools
Modified Media for Enhanced Mouse Primary Cell Culture
OPPORTUNITY Pulmonary endothelium (PE) provide vital functions in the lung and play important roles in inflammation, hemostasis, angiogenesis and regulation of vascular tone. The PE also exhibit therapeutic potential in a variety of areas such as gene therapy, cardiac regeneration, vascular graft potential, and tissue transplants. Given the importa...
Inventor(s): Anna Buford
Category(s): All Technologies, Research Tools