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Search Results - Screening+Tests

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Accurate Predictive Classification of Cystic Fibrosis Severity in Patients
Accurate Predictive Classification of Cystic Fibrosis Severity in Patients Opportunity Cystic Fibrosis (CF) is an incurable genetic disorder where cells produce excess sweat and thick mucus that can coagulate in the airway, lungs, pancreas, and other organs. When untreated, CF patients demonstrate reduced lung function, increased lung infections,...
Inventor(s): Glen Borchert, Jeffrey DeMeis
Category(s): Biomarkers, Screening Tests
Accurate Tracking and Measurement of Intercellular Mitochondrial Transfer
Opportunity Mitochondria are commonly referred to as the powerhouse of the cell, and any change in mitochondrial function can drastically alter normal cell function. Diseases including neurodegeneration and cancer have been linked to changes in mitochondrial transfer between cells, which can weaken the functioning of healthy cells. Although studying...
Inventor(s): Simon Grelet, Greg Hoover
Category(s): All Technologies, Cancer Therapeutics, Research Tools, Screening Tests
Clinical Measurement of Circulating Extracellular Vesicles in Cancer Diagnosis, Prognosis, and Treatment Response
Opportunity With vague-presenting early symptoms and a 5-year survival rate of around 10% in the USA, pancreatic cancer (PC) is difficult to diagnose early and has limited effective therapeutic options. However, if detected earlier, PC survival increases to 80%, suggesting that early detection is key to enhancing survival. Carbohydrate antigen 19-9,...
Inventor(s): Santanu Dasgupta, Ajay Singh, Kunwar Vikramdeo
Category(s): All Technologies, Screening Tests, Research Tools
Portable, Early Stage Breast Cancer Detection System
OPPORTUNITY Breast cancer is one of the most common types of cancer among women. In 2014, in the US, approximately 40,000 women died from breast cancer. The situation is much more serious in developing countries. Early detection and effective treatment are major factors contributing to the long term survival of the patient. Mammography is the current...
Inventor(s): Saeed Latif, Mohammed Alam
Category(s): Medical Device or Method, Screening Tests, Engineering Device or Method, MVP Candidate, All Technologies
Expression of Merlin Protein as a Predictive Marker for Breast Cancer Diagnosis
OPPORTUNITY The American Cancer Society’s estimates for breast cancer in the United States in 2017 that about 253,000 new cases of invasive breast cancer will be diagnosed in women. About 63,000 new cases of carcinoma in situ (CIS) will be diagnosed (CIS is noninvasive and is the earliest form of breast cancer), and about 41,000 women will die...
Inventor(s): Lalita Shevde-Samant, Rajeev Samant, Madhuri Mulekar, J. Allan Tucker
Category(s): Cancer Therapeutics, Biomarkers, Screening Tests, All Technologies
Diagnosis of intellectual disability and developmental delay
OPPORTUNITY The overall understanding of the molecular etiologies of intellectual disability (ID) and developmental delay (DD) is increasing with next-generation sequencing technologies identifying genetic variants in patients with these disorders. However, detailed analyses conclusively confirming variants, as well as the underlying molecular mechanisms...
Inventor(s): Erin Ahn, Jung-Hyun Kim, Ssang-Taek Lim
Category(s): Biomarkers, Screening Tests, All Technologies
SON Isoform Ratio for Acute Myeloid Leukemia Diagnosis
OPPORTUNITY Acute myeloid leukemia is a cancer of the blood, bone marrow and other tissues. Although treatment for acute myeloid leukemia has improved, it is only curable in 35-40% of people 60 years old or younger and in 5-15% of patients over the age of 60. Median survival of patients that do not receive intensive chemotherapy is only 5-10 months....
Inventor(s): Erin Ahn, Jung-Hyun Kim, Ssang-Taek Lim
Category(s): Biomarkers, Screening Tests, All Technologies
XRCC1 as a Predictive Biomarker for Radiation Responsiveness in Patients with Prostate Cancer
OPPORTUNITY According to statistics from the American Cancer Society, prostate cancer is the second most common cancer in American men, next to skin cancer. In 2018, it is estimated that 164,690 people will be diagnosed and about 29,430 people will die of prostate cancer. About 1 man in 9 will be diagnosed with prostate cancer during his lifetime....
Inventor(s): Eddie Reed
Category(s): Biomarkers, Cancer Therapeutics, Screening Tests, All Technologies
Methods and Compositions for Ameliorating Pancreatic Cancer
OPPORTUNITY According to statistics from the American Cancer Society, in the United States, an estimated 54,000 (28,000 men and 26,000 women) will be diagnosed and about 43,000 people (22,000 men and 21,000 women) will die of pancreatic cancer in 2017. Pancreatic cancer accounts for about 3% of all cancers in the Unite States and about 7% of all cancer...
Inventor(s): Ajay Singh, Seema Singh
Category(s): Biomarkers, Cancer Therapeutics, Screening Tests, All Technologies
Method for Screening Anti-Cancer Compounds and Detecting Cancer in Mammals
OPPORTUNITY The global market for cancer therapeutics is enormous and predicted to reach $100.6 billion in 2018 with the total revenue for the sale of anti-cancer drugs expected to continue to rise until 2022. North America dominates the industry controlling over one third of the total market share. The market comprises various classes of compounds...
Inventor(s): Gary Piazza
Category(s): Cancer Therapeutics, Screening Tests, All Technologies