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Flexible Bit Truncation Technology for Enhanced Device Efficiency and Machine Learning
Opportunity The modern world thrives on data. From personal devices like smartphones and wearables to specialized systems such as building monitors and smart appliances, data is collected, stored, and processed on a massive scale. Efficient handling of this data is critical, especially as tasks like video streaming, AI-driven applications, and machine...
Inventor(s): Na Gong, William Oswald, Jinhui Wang
Category(s): Engineering Device or Method, Software, All Technologies
Method and Kit to Detect Bacterial Infections in Blood and Urine
Opportunity Contributing to approximately $6 billion in direct health care costs each year, Urinary Tract Infections (UTIs) are the second most common infectious disease worldwide. While UTIs can range wildly in severity, they contribute significantly to cases of hospital sepsis: a life-threatening medical event caused by highly progressed infections....
Inventor(s): Allyson Shea, Rachel Fleck
Category(s): All Technologies, Biomarkers, Medical Device or Method
Accurate Tracking and Measurement of Intercellular Mitochondrial Transfer
Opportunity Mitochondria are commonly referred to as the powerhouse of the cell, and any change in mitochondrial function can drastically alter normal cell function. Diseases including neurodegeneration and cancer have been linked to changes in mitochondrial transfer between cells, which can weaken the functioning of healthy cells. Although studying...
Inventor(s): Simon Grelet, Greg Hoover
Category(s): All Technologies, Cancer Therapeutics, Research Tools, Screening Tests
Capless and Tailless Therapeutic Exogenous mRNA for Vaccine Development
Opportunity The approval and distribution of messenger RNA (mRNA) vaccines to successfully control the SARS-CoV-2 pandemic in 2021 exposed a major market for vaccine innovation and mRNA-based therapies. The mRNA used for treatment or vaccination is produced with a protecting 5’ cap and a 3’ poly-A tail at each end of the mRNA molecule....
Inventor(s): Brian Fouty, Victor Solodushko
Category(s): All Technologies, Antibody, Therapeutics, Vaccines, Gene Therapy and Delivery
Clinical Measurement of Circulating Extracellular Vesicles in Cancer Diagnosis, Prognosis, and Treatment Response
Opportunity With vague-presenting early symptoms and a 5-year survival rate of around 10% in the USA, pancreatic cancer (PC) is difficult to diagnose early and has limited effective therapeutic options. However, if detected earlier, PC survival increases to 80%, suggesting that early detection is key to enhancing survival. Carbohydrate antigen 19-9,...
Inventor(s): Santanu Dasgupta, Ajay Singh, Kunwar Vikramdeo
Category(s): All Technologies, Screening Tests, Research Tools
Computationally Constructing Peptide Sequences for Protein Signaling
Opportunity Proteins and peptides perform an array of vital functions in the human body. The variety of factors that dictate the function of a protein include its amino acid sequence, with each amino acid differentiated by a unique side chain. Specific combinations of amino acids with specific side chains join together to create proteins with unique...
Inventor(s): Aishwarya Prakash, Grant Daly, Thomas Johnsten, Ryan Benton, Thomas Johnsten
Category(s): All Technologies, Gene Therapy and Delivery, Software
N-f-MLF Derivative Peptides for the Treatment of Inflammatory Diseases
Opportunity When the body’s immune system is activated, inflammation in the affected tissue can occur. However, in some diseases, including Hyper-IgE Syndrome or Job Syndrome, unwanted inflammatory responses occur to due to continuously activated immune responses and a decreased ability to regulate them. Formyl peptide receptors (FPRs) are a...
Inventor(s): Andrew Byrd, Robert Barrington
Category(s): Therapeutics, All Technologies
Dashboard That Reduces Nurse Medication Error Risk Based on Real-Time Data
OPPORTUNITY The Institute of Medicine’s (IOM) report To Err is Human: Building a Safer Health System shocked the healthcare community when it revealed a high level of medical –and more specifically— medication errors. One of five medication administrations was identified as contributing to over 400,000 serious injuries in hospitals...
Inventor(s): Amy Campbell, Christopher Harlan, Matt Campbell
Category(s): Software, All Technologies, MVP Candidate
Novel Platform Technologies for Manufacturing Superior 3-Dimensional Fiber-Reinforced Polymer (FRP) Composite Material
OPPORTUNITY High performance composites, such as carbon fiber reinforced polymer (CFRP), are critical materials in the aerospace, defense, wind energy, automotive, and sporting goods industries. While advancements have been made in both the fabrication processes and the final products, even modern-day CFRP laminates still lack effective structural...
Inventor(s): Kuang-Ting Hsiao
Category(s): All Technologies, Composite Materials, Engineering Device or Method
Z-Aligned Fiber Reinforced Composites
OPPORTUNITY Materials can be customized by reinforcing them with rods, fibers, whiskers, and even large particles of a dissimilar material. Materials that include such enhancements are called composites. Glass fiber accounts for about 90% of the reinforcements used in composite consumption, globally. Fiber-reinforced composites are composed of axial...
Inventor(s): Kuang-Ting Hsiao
Category(s): Composite Materials, Engineering Device or Method, All Technologies
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