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Search Results - Therapeutics

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Capless and Tailless Therapeutic Exogenous mRNA for Vaccine Development
Opportunity The approval and distribution of messenger RNA (mRNA) vaccines to successfully control the SARS-CoV-2 pandemic in 2021 exposed a major market for vaccine innovation and mRNA-based therapies. The mRNA used for treatment or vaccination is produced with a protecting 5’ cap and a 3’ poly-A tail at each end of the mRNA molecule....
Inventor(s): Brian Fouty, Victor Solodushko
Category(s): All Technologies, Antibody, Therapeutics, Vaccines, Gene Therapy and Delivery
N-f-MLF Derivative Peptides for the Treatment of Inflammatory Diseases
Opportunity When the body’s immune system is activated, inflammation in the affected tissue can occur. However, in some diseases, including Hyper-IgE Syndrome or Job Syndrome, unwanted inflammatory responses occur to due to continuously activated immune responses and a decreased ability to regulate them. Formyl peptide receptors (FPRs) are a...
Inventor(s): Andrew Byrd, Robert Barrington
Category(s): Therapeutics, All Technologies
Novel Heart Attack Therapy: Caspase Inhibition Prior to Repurfusion
OPPORTUNITY Preventing heart muscle death (infarction) during a heart attack is an important goal of treatment. To this end, patients typically receive platelet inhibitors and early opening of the thrombosed artery (reperfusion), both of which aim to reduce heart muscle loss. This treatment has lowered, but not eliminated, mortality and morbidity in...
Inventor(s): Jonathon Audia, James Downey, Diego Alvarez, Michael Cohen
Category(s): Therapeutics, All Technologies